MicroRNA in HCC: Biomarkers and Therapeutic Targets

Hepatocellular carcinoma (HCC) is a malignant tumor with high morbidity and mortality. At present, diagnostic methods such as imaging observation, serum testing tissue biopsy, well treatment surgical resection, radiotherapy, chemotherapy have certain limitations in clinical interventions for HCC due to the complex pathogenesis drug resistance of liver cancer, which seriously affect survival prognosis patients. As large-scale cytokine, microRNA (miRNA) plays an important role regulating various life activities cells. Extensive evidence proved that miRNAs are specifically expressed tissues blood patients, some them been confirmed factors can participate regulation key signaling pathways cancer For this reason, these great potential diagnosis HCC, improve conventional treatment. Our paper reviews research on miRNA biomarkers targets recent years, aims provide new ideas HCC.